CHEO Research Institute Logo
Decrease Text SizeIncrease Text SizeFacebookTwitterYoutube

photo of researchers looking at an experiment
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z  

Duchenne Muscular Dystrophy 
STEADFAST Research Project 

What is Duchenne?
Duchenne muscular dystrophy (DMD) is a progressive genetic disorder that gradually weakens the body's muscles.

What is the purpose of the STEADFAST study?
The purpose of this study is to see if adding the use of a technique called “Lung Volume Recruitment" (LVR) or “breath stacking” to the usual therapy will help children with DMD cough more effectively and therefore be able to clear secretions from the lungs, throat and mouth. It can also help to maintain the ability of the chest to expand with deep breaths and may slow down the stiffening of the lungs. This is the equipment that is used to provide the LVR.
Why are we doing this research study?
We are doing this research study to try to find a way to help children with DMD to clear liquid and mucus secretions from their lungs better. We know that DMD weakens the muscles, especially the breathing muscles. Breathing complications are the main reason for sickness and death in DMD.

What does the study involve?
Children that enroll in the study are randomized to one of two groups. Group one will receive usual treatment only and Group two will receive usual treatment plus use the LVR techniques twice a day. Involvement in the study will last for 2 years.
Take Action
Quick Links

Our Researchmagnifying glass

abcefg hijklmnopqrst uvwxyz